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ABOUT US:
OUR MISSION:
To Determine the
Biological and Clinical Significance of Circulating Tumor Cells
Metastasis, the major
cause of mortality in patients with cancer, is caused by tumor cells that escape
from the primary tumor into the bloodstream and travel through the circulation
to distant sites where they develop into secondary tumors. Although these
circulating tumor cells (CTCs) provide a link between the primary tumor and
metastatic sites, the factors involved in circulating tumor cell survival in the
blood circulation and eventual metastases are not well understood.
CTCs exist in the peripheral blood of cancer patients in low
concentrations, making their isolation and identification a difficult task. Our
laboratory has developed a reliable way to detect and to characterize CTCs
isolated from the blood of cancer patients. We currently have multiple on-going
clinical trials aimed to investigate the clinical utility of CTCs.
People:
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